The main causes of acne
Acne is a chronic multifactorial disease.
Genetics as a key factor
🧬 Genetic factors influencing the development of acne
| ASPECT | DESCRIPTION |
|---|---|
| Sebum production | Genetic factors can affect the activity of the sebaceous glands, which can lead to overproduction of sebum and create an ideal environment for the development of acne. |
| Keratinization | Genetic predisposition can affect the process of skin keratinization. Excessive keratinization clogs pores and promotes the formation of comedones. |
| Hormonal sensitivity | Genes influence the sensitivity of skin receptors to androgens (e.g. DHT), which increases the reactivity of the sebaceous glands and promotes the development of inflammatory acne. |
5-alpha reductase and follicular sensitivity
The enzyme plays an important role 5-alpha reductaseThis enzyme converts testosterone to dihydrotestosterone (DHT), which stimulates sebum production. People with genetically increased activity of this enzyme are at higher risk of developing acne.
The sensitivity of hair follicles to hormones, especially DHT, is also genetically determined. Some people have follicles that are more sensitive to normal androgen levels, leading to more frequent acne breakouts.
📝 Note: These genetic aspects usually only become apparent in connection with specific triggerssuch as:
The mechanism of acne formation
💡 Tip: Although acne is a chronic disease with a genetic predisposition, proper home care can significantly to alleviate its symptoms and keep acne under control.
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